Please use this identifier to cite or link to this item: https://repositorio.ufrn.br/jspui/handle/123456789/23764
Title: Asymmetry of the temporal code for space by hippocampal place cells
Authors: Souza, Bryan C.
Tort, Adriano B. L.
Keywords: rate coding;temporal coding;hippocampus;theta phase
Issue Date: 17-Aug-2017
Resumo: Hippocampal place cells convey spatial information through spike frequency (“rate coding”) and spike timing relative to the theta phase (“temporal coding”). Whether rate and temporal coding are due to independent or related mechanisms has been the subject of wide debate. Here we show that the spike timing of place cells couples to theta phase before major increases in firing rate, anticipating the animal’s entrance into the classical, rate-based place field. In contrast, spikes rapidly decouple from theta as the animal leaves the place field and firing rate decreases. Therefore, temporal coding has strong asymmetry around the place field center. We further show that the dynamics of temporal coding along space evolves in three stages as the animal traverses the place field: phase coupling, sharp precession and phase decoupling. These results suggest that independent mechanisms may govern rate and temporal coding.
URI: https://repositorio.ufrn.br/jspui/handle/123456789/23764
Appears in Collections:ICe - Artigos publicados em periódicos

Files in This Item:
File Description SizeFormat 
AdrianoTort_ICe_2017_Asymmetry of the temporal.pdfAdrianoTort_ICe_2017_Asymmetry of the temporal2,98 MBAdobe PDFView/Open


Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.