Use este identificador para citar ou linkar para este item: https://repositorio.ufrn.br/jspui/handle/123456789/25632
Título: Memory corticalization triggered by REM sleep: mechanisms of cellular and systems consolidation
Autor(es): Almeida‑Filho, Daniel G.
Queiroz, Claudio M.
Ribeiro, Sidarta
Palavras-chave: Plasticity;Long-term memory;Ofine consolidation;Trace propagation;Cortical engagement
Data do documento: 19-Jul-2018
metadata.dc.description.resumo: Once viewed as a passive physiological state, sleep is a heterogeneous and complex sequence of brain states with essential efects on synaptic plasticity and neuronal functioning. Rapid-eye-movement (REM) sleep has been shown to promote calcium-dependent plasticity in principal neurons of the cerebral cortex, both during memory consolidation in adults and during post-natal development. This article reviews the plasticity mechanisms triggered by REM sleep, with a focus on the emerging role of kinases and immediate-early genes for the progressive corticalization of hippocampus-dependent memories. The body of evidence suggests that memory corticalization triggered by REM sleep is a systemic phenomenon with cellular and molecular causes.
URI: https://repositorio.ufrn.br/jspui/handle/123456789/25632
Aparece nas coleções:ICe - Artigos publicados em periódicos

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