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Title: A distinct class of bursting neuronswith strong gamma synchronizationand stimulus selectivity in monkey V1
Authors: Onorato, Irene
Neuenschwander, Sergio
Hoy, Jennifer
Lima, Bruss
Rocha, Katia-Simone
Broggini, Ana Clara
Uran, Cem
Spyropoulos, Georgios
Klon-Lipok, Johanna
Womelsdorf, Thilo
Fries, Pascal
Niell, Cristopher
Singer, Wolf
Vinck, Martin
Keywords: Bursting;cell class;cell type;excitatory;gamma oscillation;monkey V1;interneuron;orientation tuning
Issue Date: 12-Nov-2019
Citation: ONORATO, I.; NEUENSCHWANDER, S.; HOY, J.; LIMA, B.; ROCHA, K. S.; BROGGINI, A. C.; URAN, C.; SPYROPOULOS, G.; KLON-LIPOK, J.; WOMELSDORF, T.; FRIES, P.; NIELL, C.; SINGER, W.; VINCK, M. A distinct class of bursting neuronswith strong gamma synchronizationand stimulus selectivity in monkey V1. Neuron, v. 105, p. 1-18, nov. 2019. Doi:
Portuguese Abstract: Cortical computation depends on interactions between excitatory and inhibitory neurons. The contributions of distinct neuron types to sensory processing and network synchronization in primate visual cortex remain largely undetermined. We show that in awake monkey V1, there exists a distinct cell type (››30% of neurons) that has narrow-waveform (NW) action potentials and high spontaneous discharge rates and fires in high-frequency bursts. These neurons are more stimulus selective and phase locked to 30- to 80-Hz gamma oscillations than other neuron types. Unlike other neuron types, their gamma-phase locking is highly predictive of orientation tuning. We find evidence for strong rhythmic inhibition in these neurons, suggesting that they interact with interneurons to act as excitatory pacemakers for the V1 gamma rhythm. We did not find a similar class of NW bursting neurons in L2-L4 of mouse V1. Given its properties, this class of NW bursting neurons should be pivotal for the encoding and transmission of stimulus information.
Appears in Collections:ICe - Artigos publicados em periódicos

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