Navegando por Autor "Gonçalves, Ana Katherine da Silveira"
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TCC Avaliação da radiofrequência fracionada microablativa na composição da microbiota e maturação do epitelio vaginal: um ensaio clínico randomizado(Universidade Federal do Rio Grande do Norte, 2023-09-29) Sarmento, Ayane Cristine Alves; Gonçalves, Ana Katherine da Silveira; 0000-0002-8351-51190000-0002-8351-5119; http://lattes.cnpq.br/3436756337251449; 0000-0001-9131-1952; http://lattes.cnpq.br/6145665770763582; Santos, Raionara Cristina de Araújo; 0000-0002-5228-7707; http://lattes.cnpq.br/4471744153684640; Medeiros, Kleyton Santos de; 0000-0002-4105-7535; http://lattes.cnpq.br/3723750550570434Objetivo: Avaliar a Radiofrequência Fracionada Microablativa (RFFMA) como possível opção no tratamento da atrofia vaginal. Métodos: Trata-se de um ensaio clínico randomizado e controlado com mulheres na pós-menopausa com diagnóstico de atrofia vaginal. O tratamento consistiu em três sessões de RFFMA, comparado à administração vaginal de estrogênio e um grupo controle não tratado. As avaliações ocorreram no início e 90 dias. O desfecho primário incluiu a composição da microbiota vaginal (escore de Nugent) e a maturação das células epiteliais (valor de maturação - VM). O desfecho secundário foram eventos adversos. Resultados: Foram incluídas 120 mulheres (40 em cada grupo). O escore de Nugent foi reduzido nos grupos RFFMA e estrogênio (p< 0,01) em comparação ao grupo controle. Por fim, a VM foi modificada após tratamento com RFFMA (p<0,01) e estrogênio vaginal (p<0,001). Não houve diferenças entre os grupos RFFMA e estrogênio vaginal nas variáveis estudadas. Nenhum efeito adverso foi relatado seguindo o protocolo RFFMA. Conclusões: A radiofrequência foi comparável em eficácia à administração de estrogênio no tratamento da atrofia vulvovaginal. Merece consideração como uma opção viável no manejo dessa condição.Artigo Red meat consumption, risk of incidence of cardiovascular disease and cardiovascular mortality, and the dose–response effect(Medicines, 2019) Lima, Severina Carla Vieira Cunha; Medeiros, Gidyenne Christine Bandeira Silva de; Azevedo, Kesley Pablo Morais de; Mesquita, Gabriella Xavier Barbalho; Silva, David Franciole de Oliveira; Pimenta, Isac Davidson Santiago Fernandes; Gonçalves, Ana Katherine da Silveira; Lyra, Clélia de Oliveira; Piuvezam, Grasiela; https://orcid.org/0000-0001-8268-1986Background: Red and (particularly) processed meats are high in cholesterol and saturated and solid fatty acids. Their consumption is considered one of the risk factors for metabolic disorders. Numerous studies demonstrated a possible association between red meat consumption and cardiovascular disease (CVD). In this protocol, we propose a systematic review of the literature to examine the associations of red meat consumption with CVD incidence and mortality, and explore the potential dose–response relationship. Methods: We will search MEDLINE/PubMed, Scopus, SciELO, LILACS, ScienceDirect, Web of Science, Cochrane (CENTRAL), WHOLIS, PAHO, and Embase. We will include prospective epidemiological studies (longitudinal cohort). Risk of bias will be assessed using the Newcastle-Ottawa scale (NOS). Four independent researchers will conduct all evaluations. Disagreements will be referred to a fifth reviewer. We will summarize our findings using a narrative approach and tables to describe the characteristics of the included studies. The heterogeneity between trial results will be evaluated using a standard chi-squared test with P < .05. We will conduct the study in accordance with the guideline of the Preferred Reporting Items for Systematic Review and Meta-analyses Protocols (PRISMA-P). Results: This review will evaluate the association between red meat consumption and incidence of CVD and mortality (primary outcome measures). The secondary outcome measure will include the dose–response effect. Conclusion: The findings of this systematic review will summarize the latest evidence of the association between red meat consumption and incidence of CVD and mortality and the dose–response effect through a systematic review and meta-analysis. Registration: PROSPERO CRD42019100914. Abbreviations: CVD = cardiovascular disease, NOS = Newcastle-Ottawa scale, PRISMA = Preferred Reporting Items for Systematic Reviews and Meta-Analyzes, PRISMA-P = Preferred Reporting Items for Systematic Reviews and Meta-Analyses Protocols.Artigo Red meat consumption, risk of incidence of cardiovascular disease and cardiovascular mortality, and the dose–response effect: protocol for a systematic review and meta-analysis of longitudinal cohort studies(Medicine, 2019) Piuvezam, Grasiela; Medeiros, Gidyenne Christine Bandeira Silva de; Azevedo, Kesley Pablo Morais de; Mesquita, Gabriella Xavier Barbalho; Lima, Severina Carla Vieira Cunha; Silva, David Franciole de Oliveira; Pimenta, Isac Davidson Santiago Fernandes; Gonçalves, Ana Katherine da Silveira; Lyra, Clélia de Oliveira; https://orcid.org/0000-0002-2343-7251Background: Red and (particularly) processed meats are high in cholesterol and saturated and solid fatty acids. Their consumption is considered one of the risk factors for metabolic disorders. Numerous studies demonstrated a possible association between red meat consumption and cardiovascular disease (CVD). In this protocol, we propose a systematic review of the literature to examine the associations of red meat consumption with CVD incidence and mortality, and explore the potential dose–response relationship. Methods: We will search MEDLINE/PubMed, Scopus, SciELO, LILACS, ScienceDirect, Web of Science, Cochrane (CENTRAL), WHOLIS, PAHO, and Embase. We will include prospective epidemiological studies (longitudinal cohort). Risk of bias will be assessed using the Newcastle-Ottawa scale (NOS). Four independent researchers will conduct all evaluations. Disagreements will be referred to a fifth reviewer. We will summarize our findings using a narrative approach and tables to describe the characteristics of the included studies. The heterogeneity between trial results will be evaluated using a standard chi-squared test with P<.05. We will conduct the study in accordance with the guideline of the Preferred Reporting Items for Systematic Review and Meta-analyses Protocols (PRISMA-P). Results: This review will evaluate the association between red meat consumption and incidence of CVD and mortality (primary outcome measures). The secondary outcome measure will include the dose–response effect. Conclusion: The findings of this systematic review will summarize the latest evidence of the association between red meat consumption and incidence of CVD and mortality and the dose–response effect through a systematic review and meta-analysis