DOD - Departamento de Odontologia
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Article Immunohistochemical expression of matrix metalloproteinases 1, 2 and 9 in odontogenic myxoma and dental germ papilla(Elsevier, 2009) Nonaka, Cassiano Francisco Weege; Goulart Filho, João Augusto Vianna; Miguel, Márcia Cristina da Costa; Souza, Lélia Batista de; Pinto, Leão PereiraArticle Oral foreign body granuloma: unusual presentation of a rare adverse reaction to permanent injectable cosmetic filler(ELSEVIER, 2009) Miguel, Maria Cristina da Costa; Nonaka, C. F. W.; Santos, J. N.; Germano, Adriano Rocha; Souza, Lélia Batista deArticle Estudo imuno-histoquímico de componentes da membrana basal em cistos odontogênicos(2002) Oliveira, Marcilio Dias Chaves de; Souza, Lélia Batista de; Pinto, Leão Pereira; Freitas, Roseana de AlmeidaArticle Neurofibroma Paciniano - relato de um caso raro de localização intra-oral(2003) Souza, Lélia Batista de; Oliveira, Jamile M. B.; Freitas, Tarsila M. C.; Carvalho, Rejane A.Article Expressão imuno-histoquímica da vimentina e do HHF-35 em fibroma de células gigantes, hiperplasia fibrosa e fibroma da mucosa oral(2003) Miguel, Márcia Cristina da Costa; Andrade, Emanuel Sávio de Souza; Rocha, Danielle Albuquerque Pires; Freitas, Roseana de Almeida; Souza, Lélia Batista deThe giant cell fibroma, fibrous hyperplasia and fibroma are the most frequent fibrous oral lesions, sharing clinical and histopathological features. The purpose of this study was to investigate the immunoreactivity of the large stellate-shaped mononuclear and multinucleated cells, reported as the most characteristic histological feature of the giant cell fibroma but present occasionally in fibrous hyperplasia and fibroma, for the antibodies vimentin and HHF-35 in order to detect phenotypical characteristic of these cells. The results showed in the most of cases positive staining for vimentin, suggesting a fibroblast phenotype for these cells.Article Clinical-pathological parameters in squamous cell carcinoma of the tongue(2003) Dantas, Dilana Duarte Lima; Ramos, Carlos César Formiga; Costa, Antonio de Lisboa Lopes; Souza, Lélia Batista de; Pinto, Leão PereiraArticle Proliferating cell nuclear antigen (PCNA) and p53 protein expression in ameloblastoma and adenomatoid odontogenic tumor(SCIELO, 2005) Barbosa, Carlos Augusto Galvão; Pinto, Leão Pereira; Freitas, Roseana de Almeida; Costa, Antonio de Lisboa Lopes; Souza, Lélia Batista deArticle Evaluación clínica de la salud oral de niños con neoplasias malignas(2005) Nunez, Manuel Antonio Gordon; Pinto, Leão Pereira; Souza, Lélia Batista de; Oliveira, Patrícia TeixeiraObjective: In this descriptive study were assessment clinically children with malignant neoplasm, to evidence the correlation between oral health status and the occurrence of stomatologic complications. Patients and methods: Were evaluated the oral health conditions of 40 children with malignant neoplasm (group I) through intra and extra oral physic examination, obstention of Visible Plate Index, Gingival Bleeding Index and Decayed, Missed and Filled Teeth Index; simultaneously were observed the stomatologic complications developed in this patients. The oral health status of the children of group I was compared to the healthy children (group II). Results: The children of group I presented Gingival Bleeding Index and caries experience lower than children of group II, in other hand, the Visible Plate Index was lightly greater in children of group I, nevertheless existed statistical difference in the value of the DMF-T/dmf-t between both groups (p = 0.002). In the group I, 16 children developed together 61 stomatologic complications, with predominance of oral mucositis, followed by spontaneous oral bleeding, candidiasis and xerostomy. Conclusions: Patients in anti neoplastic therapy with deficient oral hygiene had high risk of develop stomatologic complications.Article Osteossarcoma de mandíbula inicialmente mimetizando lesão do periápice dental - relato de caso(2005) Soares, Rosilene Calazans; Soraes, Andréa Ferreira; Verde, Aldo Lima; Souza, Lélia Batista de; Pinto, Leão PereiraThe osteosarcoma is a malignant mesenchymal tumor whose cancerous cells produce osteoid matrix. It is the most common primary malignant tumor of the bone, accounting for approximately 20% of the sarcomas, but only 5% of the osteosarcomas occur in the jaws. Their aspects so clinical and histological as the course and prognostic are variable. This article shows a case report of a 20-year-old man, that presented swelling near of the mandibular left premolar. After clinical diagnostic of lesion of the dental periapex, the patient was undergone initially the endodontic treatment of the tooth involved. Thereafter, in a period of eleven days, could observe an increased considerable of the lesion resulting in visible facial asymmetry. The occlusal radiographic revealed image compatible with area radiopaque resembling sunray, suggesting diagnostic of osteosarcoma. The treatment comprised partial mandibulectomy and reconstruction of the area, using bone of the rib and graft of skin of the buttock for cover the oral mucosa involved. Eight months after surgery, there was local recurrence of the lesion and patient was death approximately one year after of its reappear.Article Tenascin and fibronectin in pleomorphic adenoma of the salivary gland(2006) Bento, Patrícia Meira; Freitas, Roseana de Almeida; Pinto, Leão Pereira; Souza, Lélia Batista deObjetivo: Analisar a expressão e o padrão de distribuição de componentes da matriz extracelular em adenomas pleomórficos de glândula salivar maior e menor e comparar os achados morfológicos destes tumores com a expressão imuno-histoquímica considerando os diferentes tipos de estromas presentes em cada caso. Métodos e Resultados: A expressão da tenascina (TN) e fibronectina (FN) foi analisada em 23 casos de adenomas pleomórficos, sendo 11 tumores em glândula salivar maior e 12 em glândula salivar menor, utilizando-se o método da estreptoavidina-biotina para os anticorpos anti-tenascina e anti-fibronectina. Os resultados imuno-histoquimicos foram correlacionados com os achados morfológicos das lesões. Todos os casos foram imunorreativos para a fibronectina mostrando forte expressão nos estromas fibrosos e condróides, embora fraca marcação tenha sido evidenciada nos estromas hialinos e mixóides. A expressão da tenascina foi mais intensa nos estromas condróides e fibrosos, sendo moderada nos estromas hialino e mixóide. Conclusões: Não houve diferença na expressão destas proteínas entre os tumores de glândula salivar maior e menor.