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Title: Fibrin rich in leukocytes and platelets (L-PRF) and bisphosphonate-induced osteonecrosis: we need to advertise now
Authors: Faria, Maria de Fátima
Cabral, Eric Lucas dos Santos
Castro, Wilkson Ricardo Silva
Florentino, Davidson Rogério de Medeiros
Costa Junior, João Florêncio da
Souza, Ricardo Pires de
Guzen, Fausto Pierdoná
Pinheiro, Francisco Irochima
Rêgo, Amália Cinthia Meneses
Araújo Filho, Irami
Keywords: Leukocyte and platelet-rich fibrin;L-PRF;Platelet-rich fibrin;Bisphosphonate-associated osteonecrosis of the jaw,;Bisphosphonate-associated osteonecrosis;Bisphosphonate related osteonecrosis of the jaw
Issue Date: 2019
Publisher: International Journal of Trend in Scientific Research and Development
Citation: FARIA, M. F.; CABRAL, E. L. S.; CASTRO, W. R. S.; FLORENTINO, D. R. M.; COSTA JUNIOR, J. F.; SOUZA, R.P.; GUZEN, F. P.; PINHEIRO, F. I.; REGO, A. C. M.; ARAUJO-FILHO, I. . Fibrin Rich in Leukocytes and Platelets (L-PRF) and Bisphosphonate-Induced Osteonecrosis: We Need to Advertise Now. International Journal of Trend in Scientific Research and Development, v. 3, p. 883-889-889, 2019. Disponível em: Acesso em: 18 mai. 2021.
Portuguese Abstract: The American Association of Oral and Maxillofacial Surgeons (AAOMS) reported in 2004 a new pathology that causes osteonecrosis in the Maxillomandibular complex. The condition was named Bisphosphonate-related osteonecrosis of the jaw (BRONJ), and later renamed by medication related to jaw osteonecrosis due to the appearance of severe alveolar bone loss in the Maxillomandibular complex resulting from the use of different drugs other than Bisphosphonates. Odontology, especially oral surgery, a field concerned with newbiotechnologies, has been introducing innovations in tissue engineering. Oro-maxillofacial reconstruction is of great interest to current oral and maxillofacial surgeons, as part of the search for strategies in bioengineering and biomaterials, a major promoter of bio-dental research in our times. In order to verify the scientific evidences to analyse the effectiveness of leukocyte and platelet rich fibrin (L-PRF) on bone neoformation inMaxillomandibular complex’s surgical procedures, a search for qualified articles was conducted in the Medline (PubMed), Embase and Cochrane Central Register of Controlled Trials databases. The works analysed were published from 2013 to 2018. This review concludes that the use of platelet rich fibrin (L-PRF) is significant in the complete healing of the lesion in short postoperative periods and in the resolution of the treatments, reducing the need for postoperative re-interventions, resulting in lower morbidity for the patients
ISSN: 2456-6470
Appears in Collections:CCS - DCIRUR - Artigos publicados em periódicos
CT - DEP - Artigos publicados em periódicos

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