Estudo piloto para ensaio clínico randomizado a avaliar orientação farmacêutica na asma

Abstract

Introduction: Asthma is a chronic disease that poses a significant health problem, affecting millions of people worldwide. Proper inhalation technique is essential for disease control, and pharmaceutical guidance has been shown to improve the effectiveness of asthma pharmacotherapy. This study aims to evaluate the feasibility of conducting a randomized clinical trial with asthmatic patients to assess the impact of pharmaceutical intervention on disease management. Methodology: A pilot study for a randomized clinical trial was conducted involving patients diagnosed with asthma. A questionnaire was administered to evaluate medication adherence, inhalation technique, and quality of life. Results: Most participants showed moderate adherence to treatment, coupled with poorly controlled disease and significant adverse events (dry mouth, nasal congestion, and headaches). Errors were identified in inhalation technique, particularly in device placement and finishing the inhalation. Quality of life was negatively impacted by mobility issues and anxiety. Conclusion: This pilot study demonstrated the feasibility of developing a randomized clinical trial to evaluate the impact of pharmaceutical intervention on asthma control. It emphasized the importance of further studies to obtain robust, relevant data to improve asthma management