Avaliação dos curativos à base de quitosana para feridas cutâneas: uma revisão

Silva, Lucas Gabriel de Medeiros da

Avaliação dos curativos à base de quitosana para feridas cutâneas: uma revisão

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dc.contributor.advisor	Lima, Ádley Antonini Neves de
dc.contributor.advisor-co1	Oliveira, Verônica da Silva
dc.contributor.advisor-co1Lattes	http://lattes.cnpq.br/3459683395706868	pt_BR
dc.contributor.advisorLattes	http://lattes.cnpq.br/4061809277935577	pt_BR
dc.contributor.author	Silva, Lucas Gabriel de Medeiros da
dc.contributor.authorLattes	http://lattes.cnpq.br/0087544261520109	pt_BR
dc.contributor.referees1	Lima, Ádley Antonini Neves de
dc.contributor.referees1Lattes	http://lattes.cnpq.br/4061809277935577	pt_BR
dc.contributor.referees2	Oliveira, Verônica da Silva
dc.contributor.referees2Lattes	http://lattes.cnpq.br/3459683395706868	pt_BR
dc.contributor.referees3	Nogueira, Fernando Henrique Andrade
dc.contributor.referees3Lattes	http://lattes.cnpq.br/3818421971151621	pt_BR
dc.contributor.referees4	Lima, Waldenice de Alencar Morais
dc.contributor.referees4Lattes	http://lattes.cnpq.br/2575667613995470	pt_BR
dc.date.accessioned	2022-07-21T17:57:51Z
dc.date.available	2022-07-21T17:57:51Z
dc.date.issued	2022-06-30
dc.description.resumo	Biopolymeric dressings are increasingly being used as an effective alternative for wound healing, since they may present multifunctional properties such as biocompatibility, low toxicity, flexibility, permeability, easy removal and many others. Although there are several biopolymers for wound healing purposes, one of the most prominent is chitosan, known it for characteristics and potential for action, such as anti-inflammatory and antimicrobial. In this context, this article aimed to investigate in vitro and in vivo studies of chitosan dressings both isolated and in associations with other components. In in vitro studies, it was possible to evaluate parameters such as biocompatibility, antimicrobial activity and release assays, confirming positive results for chitosan dressings associated with other components. In in vivo studies, it was possible to evaluate the healing potential at macroscopic and histological levels. As main results, it was observed that the wounds showed complete healing rate between 9 and 14 days, complete re-epithelialization and collagen formation. Thus, this work revealed that it is possible to develop biopolymeric chitosan dressings incorporated to other polymers or active pharmaceutical inputs, since the results are extremely satisfactory, making it a promising strategy for clinical studies in the treatment of skin lesions.	pt_BR
dc.description.sponsorship	CNPq	pt_BR
dc.description.sponsorship	CAPES	pt_BR
dc.identifier.citation	SILVA, Lucas Gabriel de Medeiros da. Evaluation of Chitosan-Based Dressings For Cutaneous Wounds: a Review. 2022. 36f. Trabalho de Conclusão de Curso (Graduação em Farmácia), Departamento de Farmácia, Centro de Ciências da Saúde, Universidade Federal do Rio Grande do Norte, Natal, 2022.	pt_BR
dc.identifier.uri	https://repositorio.ufrn.br/handle/123456789/48627
dc.language	en	pt_BR
dc.publisher	Universidade Federal do Rio Grande do Norte	pt_BR
dc.publisher.country	Brasil	pt_BR
dc.publisher.department	Departamento de Farmácia	pt_BR
dc.publisher.initials	UFRN	pt_BR
dc.publisher.program	Farmácia	pt_BR
dc.rights	Attribution-NonCommercial-NoDerivs 3.0 Brazil	*
dc.rights.uri	http://creativecommons.org/licenses/by-nc-nd/3.0/br/	*
dc.subject	polymeric dressings	pt_BR
dc.subject	skin wounds	pt_BR
dc.subject	chitosan	pt_BR
dc.subject	biological assays	pt_BR
dc.subject	wound healing	pt_BR
dc.subject	characterization techniques	pt_BR
dc.title	Avaliação dos curativos à base de quitosana para feridas cutâneas: uma revisão	pt_BR
dc.title.alternative	Evaluation of chitosan-based dressings for cutaneous wounds: a review	pt_BR
dc.type	bachelorThesis	pt_BR

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Nome:: TCC LUCAS - VERSÃO FINAL.pdf
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Descrição:: TCC LUCAS - Evaluation of Chitosan-based Dressings for Cutaneous Wounds: a review