Hippocampal and cortical communication around micro-arousals in slow-wave sleep
| dc.contributor.author | Lima, Gustavo Zampier dos Santos | |
| dc.contributor.author | Lobão-Soares, Bruno | |
| dc.contributor.author | Corso, Gilberto | |
| dc.contributor.author | Belchior, Hindiael Aeraf | |
| dc.contributor.author | Lopes, Sergio Roberto Lopes | |
| dc.contributor.author | Prado, Thiago de Lima | |
| dc.contributor.author | Nascimento, George Carlos do | |
| dc.contributor.author | Araújo, John Fontenele | |
| dc.contributor.author | Ivanov, Plamen Ch. | |
| dc.date.accessioned | 2020-12-04T19:23:10Z | |
| dc.date.available | 2020-12-04T19:23:10Z | |
| dc.date.issued | 2019-04-10 | |
| dc.description.resumo | Sleep plays a crucial role in the regulation of body homeostasis and rhythmicity in mammals. Recently, a specific component of the sleep structure has been proposed as part of its homeostatic mechanism, named micro-arousal. Here, we studied the unique progression of the dynamic behavior of cortical and hippocampal local field potentials (LFPs) during slow-wave sleep-related to motor-bursts (micro-arousals) in mice. Our main results comprised: (i) an abrupt drop in hippocampal LFP amplitude preceding micro-arousals which persisted until the end of motor-bursts (we defined as t interval, around 4s) and a similar, but delayed amplitude reduction in cortical (S1/M1) LFP activity occurring at micro-arousal onset; (ii) two abrupt frequency jumps in hippocampal LFP activity: from Theta (6–12 Hz) to Delta (2–4 Hz), also t seconds before the micro-arousal onset, and followed by another frequency jump from Delta to Theta range (5–7 Hz), now occurring at micro-arousal onset; (iii) a pattern of cortico-hippocampal frequency communication precedes micro-arousals: the analysis between hippocampal and cortical LFP fluctuations reveal high coherence during τ interval in a broader frequency band (2–12 Hz), while at a lower frequency band (0.5–2 Hz) the coherence reaches its maximum after the onset of micro-arousals. In conclusion, these novel findings indicate that oscillatory dynamics pattern of cortical and hippocampal LFPs preceding micro-arousals could be part of the regulatory processes in sleep architecture | pt_BR |
| dc.identifier.citation | LIMA, Gustavo Zampier dos Santos; LOBAO-SOARES, Bruno; CORSO, Gilberto; BELCHIOR, Hindiael; LOPES, Sergio Roberto; PRADO, Thiago de Lima; NASCIMENTO, George; FRANÇA, Arthur Cavalcanti de; FONTENELE-ARAÚJO, John; IVANOV, Plamen Ch.. Hippocampal and cortical communication around micro-arousals in slow-wave sleep. Scientific Reports, [S.L.], v. 9, n. 1, p. 5876-5876, 10 abr. 2019. Disponível em: https://www.nature.com/articles/s41598-019-42100-5. Acesso em: 20 nov. 2020. http://dx.doi.org/10.1038/s41598-019-42100-5. | pt_BR |
| dc.identifier.doi | 10.1038/s41598-019-42100-5 | |
| dc.identifier.issn | 1678-765X | |
| dc.identifier.uri | https://repositorio.ufrn.br/handle/123456789/30823 | |
| dc.language | en | pt_BR |
| dc.publisher | Nature Publishing Group | pt_BR |
| dc.rights | Attribution 3.0 Brazil | * |
| dc.rights.uri | http://creativecommons.org/licenses/by/3.0/br/ | * |
| dc.subject | Neural circuits | pt_BR |
| dc.subject | Neurophysiology | pt_BR |
| dc.title | Hippocampal and cortical communication around micro-arousals in slow-wave sleep | pt_BR |
| dc.type | article | pt_BR |
Arquivos
Pacote Original
1 - 1 de 1
Nenhuma Miniatura disponível
- Nome:
- HippocampalCortical_Lima_2019.pdf
- Tamanho:
- 3.29 MB
- Formato:
- Adobe Portable Document Format
- Descrição:
- Artigo
Nenhuma Miniatura disponível
Licença do Pacote
1 - 1 de 1
Nenhuma Miniatura disponível
- Nome:
- license.txt
- Tamanho:
- 1.45 KB
- Formato:
- Item-specific license agreed upon to submission
Nenhuma Miniatura disponível