Evidence for age-related changes in the circadian activity rhythm of the diurnal primate Callithrix jacchus: a case report

Gonçalves, Fabiana Barbosa; Borges, Galileu R.; Gonçalves, Bruno S. B.; Cavalcante, Jeferson de Souza; Menezes, Alexandre A. L.; Azevedo, Carolina Virginia Macedo de

Evidence for age-related changes in the circadian activity rhythm of the diurnal primate Callithrix jacchus: a case report

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dc.contributor.author	Gonçalves, Fabiana Barbosa
dc.contributor.author	Borges, Galileu R.
dc.contributor.author	Gonçalves, Bruno S. B.
dc.contributor.author	Cavalcante, Jeferson de Souza
dc.contributor.author	Menezes, Alexandre A. L.
dc.contributor.author	Azevedo, Carolina Virginia Macedo de
dc.date.accessioned	2020-12-16T10:25:14Z
dc.date.available	2020-12-16T10:25:14Z
dc.date.issued	2016-01-29
dc.description.resumo	Many cross-sectional studies have shown that circadian rhythms change with age, but such age-related modifications are gradual and may be insufficiently described by cross- sectional studies. In the present case study, circadian activity rhythm (CAR) was evaluated longitudinally, in both LD (12:12) and LL conditions, on two occasions in a single male marmoset: when “adult” (3 y.o.) and when “old” (9 y.o.). When adult, the CAR synchronized with positive phase angles for the onset and offset of activity. In LL, the rhythm free-ran with τ < 24 h. When old, the animal showed a significant phase delay of its activity rhythm with respect to the LD cycle (t-test, p<0.01) and a reduction on total daily activity (t-test, p<0.01), with signs of lesser stability, greater fragmentation and some loss of photic synchronization. In LL, the period free-ran with τ > 24 h. We conclude that aging attenuates photic synchronization and the expression of a circadian activity rhythm in LL in the marmoset. Further studies with a larger number of individuals are needed to confirm these findings	pt_BR
dc.identifier.citation	GONÇALVES, Fabiana Barbosa; BORGES, Galileu R.; GONÇALVES, Bruno S. B.; CAVALCANTE, Jeferson de Souza; MENEZES, Alexandre A. L.; AZEVEDO, Carolina Virginia Macedo de. Evidence for age-related changes in the circadian activity rhythm of the diurnal primate Callithrix jacchus: a case report. Biological Rhythm Research, [s. l.], v. 47, n. 3, p. 395-399, 29 jan. 2016. Disponível em: https://www.tandfonline.com/doi/abs/10.1080/09291016.2015.1129695?journalCode=nbrr20. Acesso em: 04 nov. 2020. http://dx.doi.org/10.1080/09291016.2015.1129695.	pt_BR
dc.identifier.doi	10.1080/09291016.2015.1129695
dc.identifier.issn	0929-1016
dc.identifier.issn	1744-4179
dc.identifier.uri	https://repositorio.ufrn.br/handle/123456789/31020
dc.language	en	pt_BR
dc.publisher	Taylor and Francis	pt_BR
dc.rights	Attribution 3.0 Brazil	*
dc.rights.uri	http://creativecommons.org/licenses/by/3.0/br/	*
dc.subject	Aging	pt_BR
dc.subject	Synchronization	pt_BR
dc.subject	Ontogenesis	pt_BR
dc.subject	Non-human primates	pt_BR
dc.subject	Marmoset	pt_BR
dc.title	Evidence for age-related changes in the circadian activity rhythm of the diurnal primate Callithrix jacchus: a case report	pt_BR
dc.type	article	pt_BR