Análise do ciclo sono e vigília, qualidade do sono e sonolência diurna em pessoas com a lipodistrofia congênita generalizada do nordeste do Brasil

Abstract

Berardinelli-Seip Syndrome (BSS) or Generalized Congenital Lipodystrophy of the Berardinelli-Seip type is a rare autosomal recessive disease whose main characteristic is the reduction of subcutaneous adipose tissue. The aim of this study was to evaluate the sleep/wake cycle, sleep quality and daytime sleepiness in people with Berardinelli-Seip Syndrome. The research has character transversal of quantitative analysis and was carried out in the city of Currais Novos/RN in December 2017. Ten individuals participated in the study and the data collection was performed in two stages and took place in the Association of Parents and People with Berardinelli Syndrome of the State of Rio Grande do Norte in Currais Novos. The first stage was the application of questionnaires: Epworth Sleepiness Scale, Pittsburgh Sleep Quality Index and the Health and Sleep questionnaire. The second stage was applied the sleep diary and the actimeter for 10 consecutive days. Six women and four men participated (± 29.5 years). Of these, 80% presented excessive daytime sleepiness (EDS) and 40% had poor sleep quality and the sleep pattern did not differ in the week and the weekend. Regarding sleep rhythm results, our population presented high scores in M10, L5 and intraday variability, indicating intense activity during the day, but presenting daytime sleep episode and nocturnal awakenings. As conclusion we have that subjects with BSS do not have divergence in the cycle sleep and wake during week and weekend, presenting regular activity during the day with episodes of daytime sleep, but with nocturnal agitations and awakenings, besides presenting EDS and an average borderline of poor sleep quality.

Berardinelli-Seip Syndrome (BSS) or Generalized Congenital Lipodystrophy of the Berardinelli-Seip type is a rare autosomal recessive disease whose main characteristic is the reduction of subcutaneous adipose tissue. The aim of this study was to evaluate the sleep/wake cycle, sleep quality and daytime sleepiness in people with Berardinelli-Seip Syndrome. The research has character transversal of quantitative analysis and was carried out in the city of Currais Novos/RN in December 2017. Ten individuals participated in the study and the data collection was performed in two stages and took place in the Association of Parents and People with Berardinelli Syndrome of the State of Rio Grande do Norte in Currais Novos. The first stage was the application of questionnaires: Epworth Sleepiness Scale, Pittsburgh Sleep Quality Index and the Health and Sleep questionnaire. The second stage was applied the sleep diary and the actimeter for 10 consecutive days. Six women and four men participated (± 29.5 years). Of these, 80% presented excessive daytime sleepiness (EDS) and 40% had poor sleep quality and the sleep pattern did not differ in the week and the weekend. Regarding sleep rhythm results, our population presented high scores in M10, L5 and intraday variability, indicating intense activity during the day, but presenting daytime sleep episode and nocturnal awakenings. As conclusion we have that subjects with BSS do not have divergence in the cycle sleep and wake during week and weekend, presenting regular activity during the day with episodes of daytime sleep, but with nocturnal agitations and awakenings, besides presenting EDS and an average borderline of poor sleep quality.