Manifestações patológicas bucais associadas à COVID-19: uma revisão integrativa

Abstract

Introduction: The novel coronavirus (SARS-CoV-2) has become an international public health emergency. The disease caused by it, COVID-19, systemically affects people, especially, in relation to the oral environment, as far as there is an epithelial tropism that allows the novel coronavirus to bind to the receptors of the angiotensin-converting enzyme (ACE2) present in the cells of the oral mucosa and salivary glands. This fact makes possible a direct and / or indirect relationship between this virus and oral lesions. Objective: To discuss the oral pathological manifestations that affect patients with COVID-19 in the light of articles published between January 2020 and April 2021, highlighting the relationship of the novel coronavirus with such lesions. Methodology: An integrative review based on 20 articles, of which COVID-19 descriptors, oral lesions, oral manifestations and their respective English and Spanish translations were launched as a search strategy in the databases: PubMed, Medline, Lilacs, Scopus and Web of Science, in addition to a manual search. Result: SARSCoV-2 affects patients systemically and is related to oral lesions, although it is not yet possible to be convinced whether directly or indirectly. Conclusion: It is more suggestive that such lesions are linked to factors that were triggered by the presence of SARS-CoV-2 in the organism of infected patients, however much still needs to be studied in order to know the consequences of COVID-19 in the whole organism and its direct and / or indirect action in the oral environment.