Case report: severe visceral leishmaniasis in a patient with hiv coinfection undergoing treatment for erythema nodosum leprosum

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dc.contributor.authorAquino, Samuel R.
dc.contributor.authorDiniz, Lucyo F. B.
dc.contributor.authorSilva, Igor Thiago Borges de Queiroz e
dc.contributor.authorCunha, Mirella Alves
dc.contributor.authorJusto, Alda M.
dc.contributor.authorSilva, Elis D.
dc.contributor.authorPereira, Valéria R. A.
dc.contributor.authorMedeiros, Zulma M.
dc.contributor.authorCarmo, Rodrigo F.
dc.date.accessioned2022-01-17T16:28:13Z
dc.date.available2022-01-17T16:28:13Z
dc.date.issued2020-12-02
dc.description.resumoWe report a case of visceral leishmaniasis (VL)/HIV coinfection in a patient undergoing regular antiretroviral therapy and treatment with thalidomide for erythema nodosum leprosum. He presented at a health service with high fever, chills, asthenia, pale skin, lower limb edema, hepatomegaly, and splenomegaly. Visceral leishmaniasis was confirmed by direct examination, and serological and molecular tests. Serum levels of Th1/Th2 cytokines were measured. The patient began treatment with liposomal amphotericin B, with good clinical response; however, VL recurred 6 months later. Treatment was reinitiated, maintaining secondary prophylaxis with liposomal amphotericin B. The patient showed clinical improvement with important recovery of CD4+ T-lymphocyte countpt_BR
dc.identifier.citationAQUINO, Samuel R. et al. Case Report: severe visceral leishmaniasis in a patient with hiv coinfection undergoing treatment for erythema nodosum leprosum. The American Journal Of Tropical Medicine And Hygiene, [s. l.], v. 103, n. 6, p. 2253-2256, 2 dez. 2020. American Society of Tropical Medicine and Hygiene. Disponível em: http://www.ajtmh.org/content/journals/10.4269/ajtmh.20-0567. Acesso em: 21 jan. 2021. http://dx.doi.org/10.4269/ajtmh.20-0567.pt_BR
dc.identifier.doi10.4269/ajtmh.20-0567
dc.identifier.issn0002-9637 (print)
dc.identifier.urihttps://repositorio.ufrn.br/handle/123456789/45640
dc.languageenpt_BR
dc.publisherAmerican Society of Tropical Medicine and Hygienept_BR
dc.subjectErythema Nodosumpt_BR
dc.subjectHIV Infectionspt_BR
dc.subjectLeishmaniasis, Visceralpt_BR
dc.subjectTreatment Outcomept_BR
dc.titleCase report: severe visceral leishmaniasis in a patient with hiv coinfection undergoing treatment for erythema nodosum leprosumpt_BR
dc.typearticlept_BR

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