Fibrose Cística: postura, treinamento muscular inspiratório, estigma e qualidade de vida

Abstract

Introduction: Cystic fibrosis is a multisystem disease, but with pulmonary involvement as the main cause of death. Objective: To investigate the repercussions of home inspiratory muscle training on posture, quality of life and the possible adverse effects reported by individuals with cystic fibrosis. Materials and methods: In a double-blind randomized controlled clinical trial (NCT03737630), patients of both sexes with a diagnosis of cystic fibrosis confirmed by the sweat test underwent pulmonary function test, respiratory muscle strength, postural assessment, quality of life and 3-minute step test. After that, they were divided into two groups (G40% and G20%). For the training protocol, everyone received a POWERBREATHE © and the G40% group trained with 40% of the MIP load, with load progression every week and the G20% with 20% of the MIP load without load progression for 4 weeks, 2x a day, 30 breaths. After four weeks, the individuals were reevaluated. The data were analyzed using SPSS 20.0, with a 5% significance level. The Shapiro-Wilk test was used and, according to the data distribution, the unpaired t ’test was used to compare the means between the groups. Results: Ten patients (6 men and 4 women) with a mean age of 19 ± 3.2 years were evaluated. There was a significant reduction of 6.8 cm in the T1 / T2 angle of postural assessment with a 95% confidence interval: 8.2 (0.01 - 16.3) and clinical FVC gains for both groups and FEV1 for the group G20%, considering the respective minimally important clinical differences (MICD). No major adverse effects have been reported. The other variables did not present clinical and / or significant changes. Conclusion: The protocol proposed by this study was not sufficient to generate positive effects on all variables, however due to the absence of adverse effects, it can be considered safe to be performed at home