Nutritional risk and clinical outcomes of COVID-19 in hospitalized children and adolescents: a multicenter cohort

dc.contributor.authorSilva, José Adailton da
dc.contributor.authorMello, Leilah B. de
dc.contributor.authorClemente, Heleni Aires
dc.contributor.authorBarros Neto, João A.
dc.contributor.authorMello, Carolina S.
dc.contributor.authorIDhttps://orcid.org/0000-0002-6037-7649pt_BR
dc.date.accessioned2023-12-08T16:37:56Z
dc.date.available2023-12-08T16:37:56Z
dc.date.issued2023
dc.description.resumoObjective: To verify the association between nutritional risk on admission and clinical outcomes of COVID-19 in hospitalized children and adolescents. Methods: Multicenter cohort study was conducted in two cities in the northeastern region of Brazil, with children under 18 years of age laboratory diagnosed with COVID-19. Sociodemographic data and nutritional risk screening by STRONGKids (low, medium and high risk) were collected remotely and in hospital records, respectively. The outcomes assessed were the need for ICU admission, length of stay (< 10 days or 10 days), critical cases, and death. Multivariable logistic regression models were used to evaluate the effects of high nutritional risk on COVID-19 clinical outcomes. Results: 103 individuals were evaluated, of these 35 (34.0%) had low risk, 44 (42.7%) medium risk, and 24 (23.3%) had high risk of malnutrition. In multivariate analysis, ICU bed admission (OR: 4.57; 95%CI, 1.39-4.97; p = 0.01), hospitalization longer than or equal to ten days (OR: 3.96; 95%CI, 1.22-2.83; p = 0.02) and critical cases (OR: 4.35; 95%CI, 1.08-7.55; p = 0.04) were associated with high nutritional risk. Death was not associated with high nutritional risk. Conclusions: Children and adolescents with high nutritional risk by STRONGkids at hospital admission were more likely to be admitted to the ICU, have hospitalization longer than or equal to ten days, and have critical cases when infected with SARS-CoV-2.Objective: To verify the association between nutritional risk on admission and clinical outcomes of COVID-19 in hospitalized children and adolescents. Methods: Multicenter cohort study was conducted in two cities in the northeastern region of Brazil, with children under 18 years of age laboratory diagnosed with COVID-19. Sociodemographic data and nutritional risk screening by STRONGKids (low, medium and high risk) were collected remotely and in hospital records, respectively. The outcomes assessed were the need for ICU admission, length of stay (< 10 days or 10 days), critical cases, and death. Multivariable logistic regression models were used to evaluate the effects of high nutritional risk on COVID-19 clinical outcomes. Results: 103 individuals were evaluated, of these 35 (34.0%) had low risk, 44 (42.7%) medium risk, and 24 (23.3%) had high risk of malnutrition. In multivariate analysis, ICU bed admission (OR: 4.57; 95%CI, 1.39-4.97; p = 0.01), hospitalization longer than or equal to ten days (OR: 3.96; 95%CI, 1.22-2.83; p = 0.02) and critical cases (OR: 4.35; 95%CI, 1.08-7.55; p = 0.04) were associated with high nutritional risk. Death was not associated with high nutritional risk. Conclusions: Children and adolescents with high nutritional risk by STRONGkids at hospital admission were more likely to be admitted to the ICU, have hospitalization longer than or equal to ten days, and have critical cases when infected with SARS-CoV-2.pt_BR
dc.identifier.citationSILVA, José Adailton da; ; MELLO, Leilah B. de; CLEMENTE, Heleni A.; BARROS NETO, João A.; MELLO, Carolina S.. Nutritional risk and clinical outcomes of COVID-19 in hospitalized children and adolescents: a multicenter cohort. Jornal de Pediatria, [S.L.], v. 99, n. 6, p. 641-647, nov. 2023. Elsevier BV. DOI http://dx.doi.org/10.1016/j.jped.2023.06.001. Disponível em: https://www.sciencedirect.com/science/article/pii/S0021755723000815?via%3Dihub. Acesso em: 30 nov. 2023.pt_BR
dc.identifier.doihttps://doi.org/10.1016/j.jped.2023.06.001
dc.identifier.issne1678-4782
dc.identifier.urihttps://repositorio.ufrn.br/handle/123456789/55700
dc.languageenpt_BR
dc.publisherElsevierpt_BR
dc.rightsAttribution-NonCommercial-NoDerivs 3.0 Brazil*
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/3.0/br/*
dc.subjectSARS CoV 2 infectionpt_BR
dc.subjectnutrition assessmentpt_BR
dc.subjectscreening toolpt_BR
dc.subjecthospitalizationpt_BR
dc.subjectpediatricspt_BR
dc.titleNutritional risk and clinical outcomes of COVID-19 in hospitalized children and adolescents: a multicenter cohortpt_BR
dc.typearticlept_BR

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