1. Universidade Federal do Rio Grande do Norte
2. Centro de Ciências da Saúde
3. DNUT - Departamento de Nutrição
4. CCS - DNUT - Artigos publicados em periódicos

Título:	Factors associated with increased alpha-tocopherol content in milk in response to maternal supplementation with 800 IU of vitamin E
Autor(es):	Ribeiro, Karla Danielly da Silva Rebouças, Amanda de Sousa Silva, Ana Gabriella Costa Lemos da Oliveira, Amanda Freitas de Silva, Lorena Thalia Pereira da Felgueiras, Vanessa de Freitas Cruz, Marina Sampaio Silbiger, Vivian Nogueira Dimenstein, Roberto
Palavras-chave:	Clinical trial;Lactation;Infants;Breastfeeding;Lactating women
Data do documento:	2019
Editor:	Nutrients
Referência:	REBOUÇAS, Amanda de Sousa; SILVA, Ana Gabriella Costa Lemos da; OLIVEIRA, Amanda Freitas de; SILVA, Lorena Thalia Pereira da; FELGUEIRAS, Vanessa de Freitas; CRUZ, Marina Sampaio; SILBIGER, Vivian Nogueira; RIBEIRO, Karla Danielly da Silva; DIMENSTEIN, Roberto. Factors associated with increased alpha-tocopherol content in milk in response to maternal supplementation with 800 IU of vitamin E. Nutrients, v. 11, p. 1 - 14, 2019. DOI:http://dx.doi.org/10.3390/nu11040900. Disponível em: https://www.mdpi.com/2072-6643/11/4/900. Acesso em: 07 out. 2024.
Resumo:	Background: Vitamin E supplementation might represent an efficient strategy to increase the vitamin E content in milk. The present study aimed to evaluate the impact of supplementation with 800 IU RRR-alpha-tocopherol on the alpha-tocopherol content of milk and the factors associated with the increase in vitamin E. Methods: Randomized clinical trial with 79 lactating women from Brazil, who were assigned to the control group, or to the supplemented group (800 IU of RRR-alpha-tocopherol). Milk and serum were collected between 30 and 90 days after delivery (collection 1), and on the next day (collection 2). Alpha-tocopherol was analyzed using high-performance liquid chromatography. Results: In the supplemented group, the alpha-tocopherol content in serum and milk increased after supplementation (p < 0.001). In the multivariate analysis, only alpha-tocopherol in milk (collection 1) was associated with the level of this vitamin in milk after supplementation (β = 0.927, p < 0.001), and binary logistic regression showed that the dietary intake was the only determinant for the greater effect of supplementation in milk. Conclusion: The pre-existing vitamin level in milk and diet are determinants for the efficacy of supplementation in milk, suggesting that in populations with vitamin E deficiency, high-dose supplementation can be used to restore its level in milk.
URI:	https://repositorio.ufrn.br/handle/123456789/60684
ISSN:	2072-6643
Aparece nas coleções:	CCS - DNUT - Artigos publicados em periódicos

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