Medidas de hemostasia local pós-exodontia unitárias em pacientes que fazem uso de varfarina: um estudo clínico controlado e randomizado

Abstract

The present work is a clinical trial, controlled, blinded and randomized with patients on anticoagulation therapy with warfarin comparing local hemostatic measures for the control of post-tooth extraction bleeding. For that were employed two local hemostasis methods, with group I (control) using only irrigation, compression with gauze with saline and suture and group II (study) using irrigation, compress with gauze soaked with tranexamic acid and suture. The sample consisted of 37 patients with mean age of 45,5 years and 62,2% were female. After randomization 20 were allocated to the control group and 17 in the study group, and performed a surgical procedure per patient. The surgical procedure time lasted an average of 30,9 (± 7,5) minutes. All variables that could influence the outcome were similar between the groups, no significant difference was seen (p> 0,05). In assessing the immediate hemostasis to get the stagnation of bleeding was 9,1 (± 3.6) minutes. In the study group the time to get that hemostasis was much lower compared with the control, and this difference (6,018 / IC 95%: 4,677-7,359) was statistically significant (p <0,001). Evaluating the control of bleeding mediately the use of tranexamic acid was more significantly associated with the non-occurrence of bleeding, especially in the first 24 hours. Therefore this measure of local hemostasis topic form with dressing with gauze and local irrigation was effective as a local hemostasis protocol in reducing the time of immediate hemostasis and preventing mediate bleeding.